What is Cannabigerol (CBG)?
We have all heard about CBD (cannabidiol) and THC (tetrahydrocannabinol) but the new kid on the block, is CBG. Until recently CBG, or Cannabigerol, has been a vastly unknown cannabinoid. Slowly, it is gaining traction within the health & wellness community.
- Discovered in the 1960’s this cannabinoid is actually a precursor to CBD and THC, meaning that those two cannabinoids initially start out as CBG. So really, Cannabigerol is the “mother cannabinoid”.
- Like CBD, CBG is also non-psychoactive and is full of therapeutic properties and when the two extracts are combined it elicits a much more profound effect on the endocannabinoid system (ECS) which consists of the CB1 and CB2 receptors.
- Although both CBD and CBG interact with the endocannabinoid system CBG has a much more impactful effect by directly binding onto the CB1 and CB2 receptors.
- Through a process of heat application, CBG transforms into CBD and THC, leaving behind only 1% of CBG.
- It is difficult to extract CBG by itself, which makes it a much more expensive isolate. Given this, many companies only focus on extracting CBD and THC. However, companies like Medical Mike’s have created a Organic CBG oil to ensure consumers get access to the potential benefits of this amazing, lesser-known cannabinoid.
What is the endocannabinoid system (ECS)?
ECS is responsible for maintaining homeostasis within the body such as:
- Decreasing inflammation
- Regulating immune response
- Maintaining neuron-plasticity - which reduces anxiety and depression caused by our external environment
ECS consists of two receptors:
- CB1 -receptors are found in the brain and nervous system
- CB2 -receptors are located in the immune system
Using a wide range of naturally occurring hemp cannabinoids increases the effects of those receptors and therefore helps one maintain a sense of overall well-being.
So what does CBG do?
- Multiple Sclerosis
- Irritable Bowel Disease
- Huntington’s Disease
- Potential as an antibiotic
CBG for Colorectal Cancer (CRC)
- According to a 2014 in vivo study using mouse models, published by the Oxford University Press, it was shown that CBG stopped colon cancer progression and inhibited new growth of CRC cells.
CBG for Multiple Sclerosis (MS)
- CBG has also been shown to be a potent binding anti-inflammatory agent to the CB1 and CB2 receptors when it came to neuro-inflammation.
- In a 2012 in vivo study by the Journal of Neuroimmune Pharmacology Theiler’s murine encephalomyelitis virus (TMEV), a model of multiple sclerosis (MS), was used as an experiment when using CBG.
- It was found that cannabigerol decreased the symptoms associated with TMEV and altered the gene expression involved in MS pathophysiology.
CBG for Inflammatory Bowel Disease (IBD)
- In a 2013 mouse study, CBG was administered to mice which decreased the production of white blood cells in the colitis area.
- This means that those cells were no longer required to be active in the affected areas where IBD was prominent.
- This goes to show how effective CBG is when it comes to the digestive tract.
CBG for Huntington’s Disease
- Cannabigerol also has neuroprotective qualities and can help with progression of Huntington’s Disease, a progressive brain disorder that affects movement and cognitive ability.
- A study conducted in 2015, using CBG treatment, was shown to alter and partially normalize gene expression in mice that were affected by the disease.
CBG as a potential antibiotic
- In a recent study done early this year, CBG was shown to exhibit antibiotic properties against drug-resistant bacteria.
- The study was done on mice that were infected with MRSA (methicillin-resistant Staphylococcus aureus) where vancomycin, an antibiotic, was used as an antibiotic control.
- The study demonstrated the medicinal potentials CBG can have on humans.
Does CBG have side effects?
- As of now, CBG has no known side effects but the studies are limited.
- Like CBD, CBG does not induce that feeling of being ‘high’ or intoxicated like THC.
- Higher amounts can cause feelings of euphoria and relaxation.
Taking CBG with prescribed medications
If you are taking any medications make sure to talk with your doctor before using any CBG or CBD products to avoid any adverse interactions.
Interested in trying Medical Mike’s Full Spectrum CBG oil tincture?
Shop Here: Full Spectrum CBG Oil
Question regarding our full spectrum hemp oil products? Feel free to email us: firstname.lastname@example.org